Top

Taking a novel approach to drug development

Scroll Down

Taking a novel approach to drug development

Patents

Lantern Pharma actively manages a patent portfolio that includes over 100 issued patents and pending applications across 14 patent families. This approach stand as proof of our constant innovation using A.I. and machine learning to develop cancer treatments, and our focused dedication to the progress of oncology treatments.

RADR

Method and system for predicting Blood Brain Barrier permeability

General Application
RADR

Patent Appliaion Title
Method and System for Predicting Blood Brain Barrier Permeability (PCT/US24/19851)

Patent Application Summary
Modeling BBB Permeablity

Countries

PCT

Priority Date
2024-03-14

Computerized systems and methods for ensemble model-based drug discovery

General Application
RADR

Patent Application Title
Computerized systems and methods for ensemble model-based drug discovery (PCT/US2023/064050)

Patent Application Summary
Ensemble-based modeling

Countries
Pending in US, Canada, China, EU, Korea, Australia

Priority Date
2023-03-09

Machine learning to identify gene signature response

General Application
RADR

Patent Application Title
Machine Learning to Identify Gene Signature Response

Patent Application Summary
Model methodology


Country
Pending in US

Priority Date
2021-03-01  

Identifying cancer types or subtypes suitable for treatment with a drug candidate

General Application
RADR

Patent Application Title
Identifying Cancer Types or Subtypes Suitable for Treatment with a Drug Candidate

Patent Application Summary
Model to connect subtypes with drug candidates


Countries
Pending in US

Priority Date
2021-05-18  

Gene signature of response to agent to identify tumor indications based on machine learning techniques and methods of use thereof

General Application

RADR – Drug Discovery

Patent Application Title
Gene signature of response to agent to identify tumor indications based on machine learning techniques and methods of use thereof

Patent Application Summary

Identifying drug responsiveness using scoring of one or more binary mutations.

Countries

US

Priority Date

2022-02-28

LP-300

Method for treating female non-smokers with non-small cell lung cancer

General Application
LP-300

Patent Application Title
Method for Treating Female Non-Smokers with Non-Small Cell Lung Cancer (PCT/US20/21615)

Patent Application Summary
NSCLC and Female (non/never smokers)

Countries
Pending in US, Australia, Canada, Brazil, Mexico, Japan, China, India, Singapore, Korea, EU, Hong Kong,

Priority Date
2021-09-08  

Increasing cancer patient survival time by administration of dithio-containing compounds

General Application
LP-300

Patent Title
Increasing Cancer Patient Survival Time by Administration of Dithio-Containing Compounds (14/675,607)

Patent Summary
NSCLC

Countries
US

Priority Date
2015-03-31

Method for treating female non-smokers with non-small cell lung cancer

General Application
LP-300

Patent Application Title
Method for Treating Female Non-Smokers with Non-Small Cell Lung Cancer (PCT/US20/21615)

Patent Application Summary
NSCLC

Countries
Pending in Australia, Canada, Mexico, China, Japan, US, EU, Korea, Brazil, Singapore, Hong Kong

Priority Date
2020-03-08

Method for determining sensitivity to 2,2'-dithio-bis-ethane sulfonate

General Application
LP-300

Patent Application Title
method for determining sensitivity to 2,2'-dithio-bis-ethane sulfonate  (PCT/US21/12994)

Patent Application Summary
Solid Tumors

Countries
Pending in Australia, Canada, Mexico, China, Japan, US, EU, Korea

Priority Date
2021-01-11

Anti-cancer activity augmentation compounds and formulations & methods of use thereof

General Application

Disodium 2,2’-dithio-bis-ethane sulfonate (dimensa)

Patent Title

Anti-Cancer Activity Augmentation Compounds and Formulations & Methods of Use Thereof

Patent Summary

Augmentation of anti-cancer activity

Patent No./Application No.

China ZL200780017354

Countries

China, Australia

Priority Date

2007-03-16

Compounds and methods for reducing undesired toxicity of chemotherapeutic agents

General Application

Disodium 2,2’-dithio-bis-ethane sulfonate (dimensa)

Patent Title

Compounds and Methods for Reducing Undesired Toxicity of Chemotherapeutic Agents

Patent Summary

The compositions of matter are amino acid and peptide heteroconjugated disulfides of 2-mercaptoethane sulfonate sodium.

Patent No./Application No.

US Patent Nos. 7829540, 7829539, 7829117, 7829538 & 7235589

Countries

France, UK, Denmark, and US

Priority Date

2007-03-16

Chemoprotective methods and compositions

General Application

Disodium 2,2’-dithio-bis-ethane sulfonate (dimensa)

Patent Title

Chemoprotective methods and compositions

Patent Summary

Compositions and methods for reducing, preventing, mitigating, and/or delaying the onset of, attenuating the severity of, and/or hastening the resolution of, for example, one or more chemotherapy-associated toxicities in a subject receiving one or more chemotherapeutic agents.

Patent No.

CA2648945

Countries

Australia, Canada, China, Denmark, France, Germany, Hungary, Ireland, Italy, Japan, Netherlands,  Sweden, Switzerland, and UK

Priority Date

2006-12-13

Treatment methods and compositions for lung cancer, adenocarcinoma, and other medical conditions

General Application

Disodium 2,2’-dithio-bis-ethane sulfonate (dimensa)

Patent Title

A composition containing a Formula (I) compound, administered in a medically sufficient dosage, to enhance survival and/or delay tumor progression in lung cancer patients undergoing treatment with taxane and/or platinum-based drugs.

Patent Summary

LP-300

Patent No./Application No.

US9320760

Countries

Granted in DE, GB, FR, CH, NL, DK, JP, CA, and AU, Pending in EU

Priority Date

2008-03-14

LP-184

Lyophilized illudins and analogs

General Application
LP-184

Patent Application Title
Lyophilized illudins and analogs

Patent Application Summary
LP-184/284 lyophilized products

Countries
Pending in Taiwan

Priority Date
2024-09-18

Treating liver cancers with hydroxyureamethyl acylfulvene

General Application
LP-184

Patent Application Title
Treating liver cancers with hydroxyureamethyl acylfulvene (PCT/US24/43699)

Patent Application Summary
LP-184 and liver cancer

Countries
PCT

Priority Date
2024-08-23

Cancer drug sensitivity determining markers

General Application
LP-184

Patent Application Title
Cancer drug sensitivity determining markers (PCT/US21/72496)

Patent Application Summary
Solid Tumors

Countries
Pending in US, China, Mexico, Canada, Japan,  Australia, EU, Korea

Priority Date
2021-11-18

Method for treating renal cell carcinoma or cancer

General Application
LP-184

Patent Application Title
Method for treating renal cell carcinoma or cancer (PCT/US24/19456)

Patent Application Summary
LP-184 and Renal Cancer

Countries
PCT

Priority Date
2024-03-11

Method for treating breast cancers and PARP resistant breast cancers

General Application
LP-184

Patent Application Title
Method for treating breast cancers and PARP resistant breast cancers (PCT/US23/70328)

Patent Application Summary
LP-184 and PARP Resistant Breast Cancer

Countries
Pending in US, Japan, Canada, EU

Priority Date
2023-07-17

Method for treating tumors with hydroxyureamethyl acylfulvene and radiation

General Application
LP-184

Patent Application Title
Method for treating tumors with hydroxyureamethyl acylfulvene and radiation (PCT/US2022/080150)

Patent Application Summary
LP-184 and Radiation

Countries
Pending in Australia, Canada, Mexico, Japan

Priority Date
2022-11-18

Treating cancers with combinations of PARP inhibitor and acylfulvenes

General Application
LP-184

Patent Application Title
Treating cancers with combinations of PARP inhibitor and acylfulvenes

Patent Application Summary
LP-184 and PARP Inhibitors

Countries
Pending in US, Canada, Mexico, Japan, EU

Priority Date
2022-07-29

Methods for treating cancers with spironolactone and acylfulvenes

General Application
LP-184

Patent Application Title
Methods for treating cancers with spironolactone and acylfulvenes

Patent Application Summary
LP-184 and Spironolactone

Countries
Pending in China, Mexico, Japan, EU, Australia, Korea

Priority Date
2022-07-29

Method for treating lung cancer and non-small cell lung cancer

General Application
LP-184

Patent Application Title
Method for Treating Lung Cancer and Non-Small Cell Lung Cancer (PCT/US22/71676)

Patent Application Summary
Lung cancer and NSCLC

Countries
Pending in US, Canada, Mexico, Korea, Japan, China, Australia, EU

Priority Date
2022-04-12

Method for treating rhabdoid tumor

General Application
LP-184

Patent Title
Method for treating rhabdoid tumor

Patent Summary
Rhabdoid Tumor

Countries
Granted in US, EU (Unitiary Patent), Pending in Canada, Japan, and Australia

Priority Date
2021-12-20

Treatment of brain metastasis using illudins or hydroxyureamethyl acylfulvene

General Application
LP-184

Patent Application Title
Treatment of Brain Metastasis Using Illudins or HydroxyUreaMethyl Acylfulvene

Patent Application Summary
Brain Cancer Metastatsis

Countries
Pending in US, Canada, Japan, Mexico, Brazil, China, Korea, Australia, EU

Priority Date
2022-01-10

Hydroxyureamethyl-acylfulvene for treating brain cancer or cns cancer

General Application
LP-184

Patent Application Title
Hydroxyureamethyl-acylfulvene for treating brain cancer or cns cancer (PCT/US202 l/026907)

Patent Application Summary
Brain Cancer and CNS

Countries
Pending in Japan, Canada, China, Brazil, Korea, Australia, EU, Mexico

Priority Date
2021-04-12

Method for treating pancreatic cancer

General Application
LP-184

Patent Application Title
Method for treating pancreatic cancer (PCT/US2021/031606)

Patent Application Summary
Pancreatic Cancer

Countries
Pending in Japan, Brazil, Canada, Mexico, China, Korea, Australia, EU, US

Priority Date
2021-10-05

Methods for the treatment of solid tumor cancers using illudins and biomarkers

General Application
LP-184

Patent Application Title
Methods for the Treatment of Solid Tumor Cancers Using Illudins and Biomarkers

Patent Application Summary
Solid Tumors

Countries
Pending in US, Canada, EU, Japan, China, Australia, Hong Kong

Priority Date
2018-10-14

Illudins analogs

General Application
LP-184

Patent Title
Illudins Analogs (PCT/US19/49555)

Patent Summary
LP-184 Molecule

Countries
Granted in US, India, Japan, Mexico, Pending in China, Korea, Australia, EU, Canada

Priority Date
2021-03-01  

Method for treating cancer with acylfulvene and radiation

General Application

HydroxyUreaMethyl Acylfulvene

Patent Title

Method for Treating Cancer with Acylfulvene and Radiation

Patent Summary

This is application is directed to methods for treating Cancers by administration of HydroxyUreaMethyl Acylfulvene with radiation doses.

Countries

EU, US

Priority Date

11/18/2022

Illudin analogs useful as anticancer agents

General Application

Irofulven

Patent Title

Illudin analogs useful as anticancer agents

Patent Summary

acylfulvene analogs, which inhibit tumor growth, especially solid tumor growth, and which have an adequate therapeutic index to be effective for in vivo treatment

Patent No./Application No.

US7655695

Countries

EP1909783B1 (Germany, France, and Great Britain), JP4989648 (US is Priority Application)

Priority Date

2010-02-02

Illudin analogs, used thereof, and methods for synthesizing the same

General Application

Next Generation Illudins

Patent Application Title

Illudin analogs, used thereof, and methods for synthesizing the same

Patent Application Summary

This application is directed to illudin derivatives or analogs, intermediates, preparation methods, pharmaceutical compositions and uses thereof.  A new and potentially more potent illudin is disclosed in this application.

Patent No./Application No.

PCT/US19/49555

Countries

Granted in US, Japan, Mexico, Pending in EU, Canada, India, China, Korea

Priority Date

2019-09-04

LP-284

Illudins analogs

General Application
LP-284

Patent Title
Illudins analogs (PCT/US19/49555)

Patent Summary
LP-184 / 284 Molecule

Countries
Granted in US, India, Japan, Mexico, Pending in China, Korea, Australia, EU, Canada

Priority Date
2021-03-01

Illudin analogs, uses thereof, and methods for synthesizing the same

General Application

Next Generation Illudins

Patent Application Title

Illudin analogs, used thereof, and methods for synthesizing the same

Patent Application Summary

This application is directed to illudin derivatives or analogs, intermediates, preparation methods, pharmaceutical compositions and uses thereof.  A new and potentially more potent illudin is disclosed in this application.

Patent No./Application No.

PCT/US19/49555

Countries

Granted in US, Japan, Mexico, Pending in EU, Canada, India, China, Korea

Priority Date

2019-09-04

Lyophilized illudins and analogs

General Application
LP-284

Patent Application Title
Lyophilized illudins and analogs

Patent Application Summary
LP-184/284 lyophilized products

Countries
Pending in Taiwan

Priority Date
2024-09-18

Treating cancers with combinations of acylfulvenes with ibrutinib and/or bortezomib

General Application
LP-284

Patent Application Title
Treating cancers with combinations of acylfulvenes with ibrutinib and/or bortezomib (PCT/US2023/024759)

Patent Application Summary
LP-284 and Ibrutinib/bortezomib

Countries
Pending in US, Japan, Canada, China, Australia, Mexico, EU

Priority Date
2023-06-07

Methods for treating cancers with spironolactone and acylfulvenes

General Application
LP-284

Patent Application Title
Methods for treating cancers with spironolactone and acylfulvenes

Patent Application Summary
LP-284 and Spironolactone

Countries
Pending in China, Mexico, Japan, EU, Australia, Korea

Priority Date
2022-07-29

Method for treating blood cancers

General Application

Positive HydroxyUreaMethyl Acylfulvene

Patent Application Title

Method For Treating Blood Cancers

Patent Application Summary

LP-284 and Blood Cancers

Countries

Pending in Australia, US

Priority Date

2022-05-03

"We are in the golden age of A.I. where we are able to significantly impact the speed and precision at which we develop new drugs."
Panna Sharma
PRESIDENT & CEO, LANTERN PHARMA

By clicking “Accept All”, you agree to the storing of cookies on your device to enhance site navigation, analyze site usage, and assist in our marketing efforts. View our Privacy Policy for more information.